Wolman's disease

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Wolman disease - a rare disease of the lipid group, caused by a deficiency in cholesterol esterase. Appearance in adolescence is primary hypothyroidism. The clinical picture consists of multiple organ dysfunctions (including large calcifications in both adrenal glands, hepatosplenomeglia) caused by cholesterol metabolism disorders. Regardless of the treatment leads to death. The disease was described by Israeli neuropathologist Moshe Wolman et al. In 1961.

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