Laktamy


β-lactam, γ-lactam, δ-lactam ε-lactam

Laktamy - so called. "intramolecular amides" heterocyclic compounds containing a ring nitrogen atom and a carbonyl group in position 2 relative to the nitrogen atom. You can get them. on the way [2 + 2] the cyclization of ketene with nitrile or the rearrangement of d-4-isoxazoline. The condition for the lactam to be formed is that the amino group found in the original compound was at gamma carbon (carbon at position four from carboxy) or further.

The lactam ring is a component of many antibiotics.

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