Kennedy's disease

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Kennedy's disease (Kennedy's disease, X-linked spinal and bulbar muscular atrophy, SBMA, SMAX1) is a genetic disease manifested by chronic weakness, muscle atrophy, fascination, skin thinning and hyporeflexia. The cause of the disease is the expansion of CAG trinucleotide repeats in intron 1 of the androgen receptor gene. Mutations in this gene (but not the nature of the increase in the number of nucleotides) may cause an androgen depletion syndrome, so it is an allelic disease.

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